AbClon
제품 및 취급브랜드
Atlas Antibodies
Atlas Antibodies는 인간단백질을 대상으로 인간 단백질 지도를 만들기 위해 4,000억원의 개발비가 투입된
전 세계 최대의 항체프로젝트인 Human Protein Atlas(HPA) 프로그램을 통해 개발, 검증 된 고품질의 항체를
이용하여 단백질을 연구하는 연구자들에게 Normal과 Cancer 조직에 대한 이미지와 함께 제공하고 있습니다.
- 인간 유전자에 대한 21,000개 이상의 항체 제공
- 인간의 전체 단백질에 대한 항체를 공급하는 유일한 제품
- Sigma-Aldrich Prestige Antibodies와 동일 제품(Sigma-Aldrich에 OEM 납품)
- 소요기간 : 1 ~ 2 주
-
- DB검색
- www.proteinatlas.org
-
다양한 Application 정상조직 및 암 조직을 이용한 단백질 발현 정보 제공
www.proteinatlas.org 는 단백질 발현의 상세정보를 제공하고 있습니다.
Gene Information
Gene And Protein Data
| Gene name | CD44 (HGNC Symbol) |
|---|---|
| Synonyms | CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1 |
| Description | CD44 molecule (Indian blood group) (HGNC Symbol) |
| Entrez gene summary | The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008 |
| Chromosome | 11 |
Tissue Atlas
Normal Tissue Data
| Gene description | CD44 molecule (Indian blood group) |
|---|---|
| RNA tissue category | Expressed in all |
| Protein summary | Detected at High or Medium expression levels in 33 of 82 analyzed normal tissue cell types. |
| Protein expression | Cytoplasmic and membranous staining in most epithelial and lymphatic tissues |
| Protein class | Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins |
| Predicted localization | Membrane,Secreted |
| Protein evidence | Evidence at protein level |
| Protein reliability | Supportive based on 3 antibodies |
Subcell Atlas - Human
Subcellular Data
 |
Summary | Mainly localized to the plasma membrane but also to the Golgi apparatus. |
|---|---|---|
| Main location | Plasma membrane | |
| Additional location | Golgi apparatus | |
| Reliability | Supportive | |
| Protein evidence | Evidence at protein level | |
| Assay summary | Analysis based on three antibodies, CAB000112, CAB000316 andHPA005785, using immuno-fluorescence in human cells |
Cell Line Atlas
Cell Line Summary
 |
Gene description | CD44 molecule (Indian blood group) |
|---|---|---|
| RNA expression | Transcript detected at medium/high level in 28 cell lines | |
| Protein expression | Protein detected at medium/high level in 26 cell lines | |
| Protein class | Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins | |
| Reliability | Supportive |
Cancer Atlas
Cancer Tissue Data
| Summary | CD44 molecule (Indian blood group) |
|---|---|
| Protein class | Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins |
| Protein evidence | Evidence at protein level |
