앱클론 AbClon 서비스

Atlas Antibodies는 인간단백질을 대상으로 인간 단백질 지도를 만들기 위해 4,000억원의 개발비가 투입된
전 세계 최대의 항체프로젝트인 Human Protein Atlas(HPA) 프로그램을 통해 개발, 검증 된 고품질의 항체를
이용하여 단백질을 연구하는 연구자들에게 Normal과 Cancer 조직에 대한 이미지와 함께 제공하고 있습니다.

인간 유전자에 대한 21,000개 이상의 항체 제공
인간의 전체 단백질에 대한 항체를 공급하는 유일한 제품
Sigma-Aldrich Prestige Antibodies와 동일 제품(Sigma-Aldrich에 OEM 납품)
소요기간 : 1 ~ 2 주

DB검색

www.proteinatlas.org
제품검색

www.atlasantibodies.com

다양한 Application 정상조직 및 암 조직을 이용한 단백질 발현 정보 제공

www.proteinatlas.org 는 단백질 발현의 상세정보를 제공하고 있습니다.

Gene Information

Gene And Protein Data

Gene Information
Gene name	CD44 (HGNC Symbol)
Synonyms	CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1
Description	CD44 molecule (Indian blood group) (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008
Chromosome	11

Tissue Atlas

Normal Tissue Data

Tissue Atlas
Gene description	CD44 molecule (Indian blood group)
RNA tissue category	Expressed in all
Protein summary	Detected at High or Medium expression levels in 33 of 82 analyzed normal tissue cell types.
Protein expression	Cytoplasmic and membranous staining in most epithelial and lymphatic tissues
Protein class	Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Predicted localization	Membrane,Secreted
Protein evidence	Evidence at protein level
Protein reliability	Supportive based on 3 antibodies

Subcell Atlas - Human

Subcellular Data

Subcell Atlas - Human
	Summary	Mainly localized to the plasma membrane but also to the Golgi apparatus.
	Main location	Plasma membrane
	Additional location	Golgi apparatus
	Reliability	Supportive
	Protein evidence	Evidence at protein level
	Assay summary	Analysis based on three antibodies, CAB000112, CAB000316 andHPA005785, using immuno-fluorescence in human cells

Cell Line Atlas

Cell Line Summary

Cell Line Atlas
	Gene description	CD44 molecule (Indian blood group)
	RNA expression	Transcript detected at medium/high level in 28 cell lines
	Protein expression	Protein detected at medium/high level in 26 cell lines
	Protein class	Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
	Reliability	Supportive

Cancer Atlas

Cancer Tissue Data

Cancer Atlas
Summary	CD44 molecule (Indian blood group)
Protein class	Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Protein evidence	Evidence at protein level

AbClon

주메뉴

제품 및 취급브랜드

Atlas Antibodies