In-vitro Efficacy
AbClon has a variety of cell lines for analyzing the efficacy of drugs and has a wide range of analytical experience, especially for antibody drugs. AbClon provides reliable assay results using cell lines from the ATCC and validated through the Mycoplasma test.
Cell line list
Cell line list
No |
Cell name |
Species |
origin |
Xenograft setting |
1 |
Reh |
Hu |
acute lymphocytic leukemia |
|
2 |
RPMI 8226 |
Hu |
B cell; B lymphocyte |
|
3 |
Raji |
Hu |
B lymphocyte |
|
4 |
TF-1 |
Hu |
Bone marrow |
|
5 |
K-562 |
Hu |
Bone marrow |
|
6 |
RS4;11 |
Hu |
Bone marrow |
|
7 |
BT-474 |
Hu |
breast |
|
8 |
HCC-1569 |
Hu |
breast |
Yes |
9 |
HCC1954 |
Hu |
breast |
Yes |
10 |
HCC202 |
Hu |
breast |
|
11 |
MCF-7 |
Hu |
breast |
|
12 |
MDA-MB-231 |
Hu |
breast |
Yes |
13 |
MDA-MB-453 |
Hu |
breast |
Yes |
14 |
SK-BR-3 |
Hu |
breast |
|
15 |
T-47D |
Hu |
breast |
Yes |
16 |
UACC-893 |
Hu |
breast |
|
17 |
HeLa |
Hu |
cervix |
|
18 |
HCT116 |
Hu |
colon |
|
19 |
HCT15 |
Hu |
colon |
|
20 |
HT-29 |
Hu |
colon |
Yes |
21 |
SW403 |
Hu |
colon |
Yes |
22 |
SW48 |
Hu |
colon |
Yes |
23 |
SW480 |
Hu |
colon |
|
24 |
LS 174T |
Hu |
colon |
Yes |
25 |
CT26.WT |
Ms |
colon |
|
26 |
HCC-1419 |
Hu |
ductal cancer |
|
27 |
HCC-2218 |
Hu |
ductal cancer |
|
28 |
HGC-27 |
Hu |
Gastric cancer undifferentiated, mucin producing |
|
29 |
NUGC-4 |
Hu |
gastric lymph node |
|
30 |
Phoenix-ECO |
Hu |
kidney |
|
31 |
PG13 |
Ms |
Leukemia |
|
32 |
HCC827 |
Hu |
Lung |
Yes |
33 |
NCI-H358 |
Hu |
Lung |
Yes |
34 |
A549 |
Hu |
Lung |
Yes |
35 |
NCI-H1650 |
Hu |
Lung |
Yes |
36 |
Calu-3 |
Hu |
Lung |
|
37 |
MRC-5 |
Hu |
Lung |
|
38 |
ZR-75-1 |
Hu |
mammary gland/breast |
|
39 |
ZR-75-30 |
Hu |
mammary gland/breast |
|
40 |
AU565 |
Hu |
mammary gland/breast |
|
41 |
SK-OV-3 |
Hu |
ovary |
Yes |
42 |
BxPC-3 |
Hu |
pancreas |
Yes |
43 |
Capan-2 |
Hu |
pancreas |
|
44 |
THP-1 |
Hu |
Peripheral blood |
|
45 |
FaDu |
Hu |
pharynx |
Yes |
46 |
A431 |
Hu |
skin |
Yes |
47 |
KATO III |
Hu |
stomach |
|
48 |
MKN-45 |
Hu |
stomach |
|
49 |
MKN7 |
Hu |
stomach |
|
50 |
SNU-216 |
Hu |
stomach |
|
51 |
SNU-1 |
Hu |
Rabbit |
|
52 |
NUGC-3 |
Hu |
stomach |
|
53 |
SNU-520 |
Hu |
stomach |
|
54 |
OE-19 |
Hu |
stomach/Oesophagus |
Yes |
55 |
NCI-N87 |
Hu |
Stomach:Liver |
Yes |
56 |
Hs 746T |
Hu |
stomach; derived from metastatic site: left leg |
|
57 |
Jurkat, clone E6-1 |
Hu |
T lymphocyte |
|
58 |
EC-RF24 |
Hu |
Umbilical Cord |
|
AbClon provided
In-vivo Efficacy (Xenograft)
In order to confirm the in vivo activity of anticancer drugs, Xenograft mouse model for major cell lines has have been set up as a useful test method for transplanting human cancer cells into immunoimmune-deficient mice to induce tumors and evaluate the efficacy after drug treatment. Setting the test method is also available.
Summary