AbClon

The Octet analysis system is a fast and accurate measure of antibody binding affinity (KD). Eight samples can be analyzed at the same time, easy sorting of antibodies by K-off ranking, and accurate measurement of antibody affinity change during humanization and affinity maturation.

Octet analysis can measure binding affinity between antibody and antigen as well as binding affinity between ligand and receptor. It is also used for antibody characterization such as epitope binning.

Octet analysis is based on BioLayer Interferometry (BLI) technology, which uses the difference in length of the white light wavelengths reflected from the internal reference layer and the two surfaces of the immobilized protein layer.