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Atlas Antibodies researches proteins using high-quality antibodies developed and validated through
the Human Protein Atlas (HPA) program, the world's largest antibody project with a cost of 400
billion won to create human protein maps for human proteins Researchers are provided with
images of normal and cancer tissues.

More than 18,000 antibodies to human genes
The only product that provides antibodies to the entire human protein
Same product as Sigma-Aldrich Prestige Antibodies (OEM delivered to Sigma-Aldrich)
Duration: 1 ~ 2 weeks

Search DB

www.proteinatlas.org
Product search

www.atlasantibodies.com

Various applications Information on protein expression using normal tissue and cancer tissue

www.proteinatlas.org provides detailed information on protein expression.

Gene Information

Gene And Protein Data

Gene Information
Gene name	CD44 (HGNC Symbol)
Synonyms	CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1
Description	CD44 molecule (Indian blood group) (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008
Chromosome	11

Tissue Atlas

Normal Tissue Data

Tissue Atlas
Gene description	CD44 molecule (Indian blood group)
RNA tissue category	Expressed in all
Protein summary	Detected at High or Medium expression levels in 33 of 82 analyzed normal tissue cell types.
Protein expression	Cytoplasmic and membranous staining in most epithelial and lymphatic tissues
Protein class	Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Predicted localization	Membrane,Secreted
Protein evidence	Evidence at protein level
Protein reliability	Supportive based on 3 antibodies

Subcell Atlas - Human

Subcellular Data

Subcell Atlas - Human
	Summary	Mainly localized to the plasma membrane but also to the Golgi apparatus.
	Main location	Plasma membrane
	Additional location	Golgi apparatus
	Reliability	Supportive
	Protein evidence	Evidence at protein level
	Assay summary	Analysis based on three antibodies, CAB000112, CAB000316 andHPA005785, using immuno-fluorescence in human cells

Cell Line Atlas

Cell Line Summary

Cell Line Atlas
	Gene description	CD44 molecule (Indian blood group)
	RNA expression	Transcript detected at medium/high level in 28 cell lines
	Protein expression	Protein detected at medium/high level in 26 cell lines
	Protein class	Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
	Reliability	Supportive

Cancer Atlas

Cancer Tissue Data

Cancer Atlas
Summary	CD44 molecule (Indian blood group)
Protein class	Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Protein evidence	Evidence at protein level

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Atlas Antibodies